Cholesterol-lowering drugs may accelerate onset of Parkinson's disease, according to researchers

Patients with cholesterol problems are also at risk for cardiovascular disease and commonly prescribed a statin (A cholesterol-reducing medication). 



It may relieve the heart from some issues, but the brain not so. At the Penn State College of Medicine, a study conducted by researchers discovered a shocking fact about the medications: statin use can increase a person’s chance off developing Parkinson’s disease. 



In the study, researchers released and examine data from a database filled with insurance claims. In it, 50 million people were registered, and but were only able to identify 22,000 people who suffered from Parkinson’s disease. 

The number was lowered to 2,322 people who had been diagnosed recently with Parkinson’s. The patients had been paired up with another person from the database who didn’t suffer from Parkinson’s disease. The researchers then assessed who took a statin, and how long it took for symptoms to be clearly seen. 

Movement Disorders published the results, which prove there Is a link between statin use and Parkinson’s disease. In that study, researchers made note that the risk for Parkinson’s was higher during the beginning of statin treatment, around 2 1/2 years exactly. The link to the disease was much stronger in statins that disperse in fat, or lipophilic statins. 

This is caused mostly by statin’s ability to enter many tissues in the body. In comparison to water-dissolving, or hydrophilic, statins, lipophilic statins can penetrate easily, meaning they can travel to the brain when hydrophilic statins are unable to. It’s certain that lipophilic statins can harm brain cells and cause deterioration. Despite the findings, researchers note that more investigation was needed. The study didn’t include Medicare-covered patients, and didn’t acknowledge patients over the age of 65. 

What is Parkinson’s disease?


Parkinson’s disease is an aggressive and chronic neurodegenerative brain disorder that impairs movement. This happens when brain cells or neurons stop working to produce dopamine, the chemical that controls movement. When someone has low dopamine levels, the more likely they aren’t having control of their movements. Walking issues, tremors, and slow movement is some of the symptoms associated with Parkinson’s disease, and only worsen over time. 

No cure is available at the moment for Parkinson’s, or cause that helps to understand how it develops. What can be done, is for patients to be provided with treatments based on symptoms they experience. The treatment methods can range from medication to lower the severity of symptoms, or surgery in the case that all remedies have been used, especially occupational and physical therapy. 






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Cholesterol-lowering drugs may accelerate onset of Parkinson's disease, according to researchers Cholesterol-lowering drugs may accelerate onset of Parkinson's disease, according to researchers Reviewed by Jamm Real on 14:18:00 Rating: 5
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