Creating Babies Without Eggs May One Day Be Possible Thanks To Groundbreaking New Research

In an incredible experiment that could revolutionize embryology, scientists have been able to create offspring by implanting something other than an egg with sperm, It is suggested that the new findings could pave the way for using skin cells instead of eggs for fertility treatment.

Molecular embryologist Dr Tony Perry, the senior author of the study published in Nature Communications explains In effect, they have found a different way to make an embryo, hinting that eggs may not be unique in their ability to do so.

Our work challenges the dogma, held since early embryologists first observed mammalian eggs around 1827 and observed fertilisation 50 years later, that only an egg cell fertilised with a sperm cell can result in a live mammalian birth.

In normal circumstances, for an egg to develop into an embryo, it has to be fertilized by its paramorical sperm cell.  For the first time however, researchers have managed to “trick” mouse eggs into developing without this fertilization. These resulting embryos are known as parthenogenotes, that are no longer eggs - they behave in a similar way to normal skin cells in the body. These parthenogenotes were then injected with sperm, and instead of dying, the cells started to develop as normal, eventually becoming healthy baby mice pups.

Incredibly, the success rate of this procedure was a staggering 24%, far higher than the survival rate of parthernogenotes, which is 0%,  and for nuclear transfer cloning, which is 2%. Furthermore, the resulting 30 pups from the experiment seemingly have no untoward health problems, with some of them even going on to have their own babies, which in turn have had their own.

Although there is still a long way to go before scientists are able to use skin cells instead of eggs, something which they are not even certain can actually be achieved.

The implications could be huge.

It would mean that women who are infertile for a number of reasons, such as through age or from harsh chemotherapy, could still have children. It would also mean that gay couples who wish to have children would also be able to produce embryos between themselves.

The benefits would not only be limited to humans, either, as it would enable conservationists to help save endangered creatures. Using skin cells instead of eggs could massively help rare animals, forming a different way to produce embryos that could then be implanted into surrogate mothers.

The researchers do still stress:

Any such advancement is still “speculative and fanciful”, but it gives a clear starting point, and suggests that the fate of a cell is nowhere near as concrete as originally thought.

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Creating Babies Without Eggs May One Day Be Possible Thanks To Groundbreaking New Research Creating Babies Without Eggs May One Day Be Possible Thanks To Groundbreaking New Research Reviewed by Admin on 23:51:00 Rating: 5
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